A comparative clinical study of cefaclor with cephalexin was carried out by randomized double blind techniques in order to compare the clinical efficacy, side effects and usefulness in treatment. The in-vitro dissolution studies of fexofenadine hydrochloride 120 mg tablets were carried out 01n hcl for 10 and 30 minutes using usp-ii method three samples showed more than 60% drug release within 10 minutes and more than 80% drug release within 30 minutes. (1998) development of in vitro susceptibility testing criteria and quality control parameters tentative guideline ( national committee for clinical laboratory standards , wayne, pa ), 3rd ed pp m23 - t3. Keflex® (cephalexin) capsules, usp is a semisynthetic cephalosporin antibacterial drug intended for oral administration it is 7-(d-α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid monohydrate. Stephen fowler and hongjian zhang, in vitro evaluation of reversible and irreversible cytochrome p450 inhibition: current status on methodologies and their utility for predicting drug-drug interactions, the aaps journal, 10, 2, (410), (2008.
A total of 893 isolates, consisting of 393 staphylococci, 228 streptococci, 210 h influenzae and 62 strains of s typhi were used to evaluate the in vitro activity of azithromycin and the results were compared with erythromycin, ampicillin, augmentin and cephalexin (table. Procedure of dissolution study: the in vitro dissolution studies of cephalexin extended-release tablets were performed using usp type i dissolution apparatus (basket type) (electrolabs, india) the dissolution medium consisted of 900 ml of 001n hcl (1 st h) and phosphate buffer (ph=68) during the rest of the study period maintained at 37±02°c. Before therapy with cephalexin capsules is instituted, inquire whether the patient has a history of hypersensitivity reactions to cephalexin, cephalosporins, penicillins, or other drugs cross-hypersensitivity among beta-lactam antibacterial drugs may occur in up to 10% of patients with a history of penicillin allergy. Review of the literature identified pharmacokinetic studies of cefpodoxime 5 and cephalexin 6-11,e,f in dogs that were used for comparison with the pharmacokinetics of the present study for cephalexin, mean t 1/2 and c max were longer and higher, respectively, for the study reported here.
Ehsan adeli, irbesartan‐loaded electrospun nanofibers‐based pvp k90 for the drug dissolution improvement: fabrication, in vitro performance assessment, and in vivo evaluation, journal of applied polymer science, 132, 27, (2015. International journal of pharmaceutical sciences and research, 2012, 3(2): 545-550 mikre w, ashenef a and mekonnen n comparative evaluation of the in vivo and in vitro characteristics of different brands of paracetamol tablets, ethiopian pharmaceutical journal, 2000 18, 43-53. Nitrofurantoin, sulfamethizole and cephalexin peak urinary drag concentrations were studied in patients and non-human primates with unequally functioning pyelonephritie kidneys.
Mikre w, ashenef a and mekonnen n comparative evaluation isolates from urinary tract infections at felege hiwot referral of the in vivo and in vitro characteristics of different brands of hospital, ethiopia. During development, in quality control and for post approval changes, in vitro dissolution testing is an important part of stability studies after the approval of a new drug, commonly, only one test model is utilized for routine in vitro quality control dissolution testing. Comparative in vitro quality evaluation of some paracetamol tablets, commercially available in bangladesh drug market uploaded by baru chandrasekhar rao paracetamol is a widely used non-prescription analgesic and antipyretic medicine.
The study was conducted to assess the comparative in-vitro quality control parameters through the evaluation of weight variation, hardness, friability, disintegration time and dissolution profile between the commercially available tablet brands of paraceta-mol and paracetamol/caffeine combination in bangladesh. The in vitro activities of five cephalosporin antibiotics against 121 strains of salmonellae were compared, cefamandole and cefaclor were more potent than cefazolin, and these three drugs were more active than cephalothin and cephalexin. Guidance for industry: extended release oral dosage forms: development, evaluation, and application of in vitro/in vivo correlations us department of health and human services, food and drug administration, center for drug evaluation and research (cder), september 1997.
Volume 2, issue 4 . The study was exclusively experimental that used bp, usp and other standard books to check the in vitro quality of paracetamol tablet using different analytical techniques and procedure test for weight variation, friability, disintegration time, identification test and assay were conducted. Cephalexin was evaluated in vitro and in the treatment of urinary tract infection the drug was absorbed well and excreted in the urine in high concentrations urine levels of cephalexin were adequate to inhibit more than 90% of escherichia coli, proteus mirabilis , and klebsiella pneumoniae strains. The quality control department the in vitro dissolution studies of cephalexin extended-release tablets were formulation and evaluation of cephalexin extended.
Evaluation and comparison of in-vitro dissolution profiles for different brands of amoxicillin capsules l kassaye and g genete food and medicine quality control laboratory, food, medicine and healthcare administration and control authority, ethiopia, addis ababa. Evaluation of in vitro dissolution qualities of various commercially available paracetamol tablet samples paracetamol tablets of 500 mg were chosen for the study.
Comparative evaluation of lithium disilicate ceramic surface and bond strength to dentin surface after treatment with hydrofluoric acid and acidulated phosphate fluoride gel-an in-vitro study 6 on the understanding of zoe cement use prior to etch-rinse bonding strategies. Quality of medicine is an absolute necessity in terms of both therapeutic efficacy and safety of the patients world health organization claimed that the manufacturers must undertake responsibility for the quality of the medicines that they manufacturing [ 3 . Simultaneous in vitro and in vivo evaluation of both trimethoprim and sulfamethoxazole from certain dosage forms dissolution profiles for multisized prednisolone acetate suspensions 15.